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My Wild Dreams

Health & Fitness > School Children Were the Clinical Trial Patients.
 

School Children Were the Clinical Trial Patients.

Today, before a drug can be approved for use with the general public, it usually has to go through a long and laborious testing period and can only be used in clinical trials.

But back in the early 50's,  the children of the United States became the "clinical trial" for a scourge that kept parents living in fear, especially during the summer months.  That  disease was, of course, polio or infantile paralysis.


Every city had a hospital filled with iron lungs where people received round the clock care.
Hardly a family was untouched by this horrible disease that left so many permanently paralyzed or crippled for life. I personally had two cousins and a classmate who contracted the illness.   One was left permanently disabled.  Though the disease did strike adults too, it was far more prevalent in children.  At its very worst, it could shut down the respiratory system, forcing people to live their lives in iron lungs.

The frightening thing was that no one knew how the disease spread.  Parents were at a loss as to how to protect their children.

We all freely gave our dimes and more--children and parents alike--to the March of Dimes to fund research to find a cure or a vaccine against it.
March of Dimes cards sat in restaurants, drug stores, and many other places to remind people to give their change.
In 1955, Dr. Jonas Salk, working at the University of Pittsburgh and funded by the March of Dimes, believed he had found a vaccine after eight long years of trial and error.  

He tested it on his own family and they immediately began developing antibodies against the disease.

When he announced it to the world, within months health officials began arriving at public schools to immunize children. 

They had no idea how effective it was going to be. However, the public began demanding that their children be given the shot just as soon as possible.

I still remember when they arrived at my school and I received the first of three immunizations.

Because the vaccine was a dead virus, it posed no threat of actually causing the person to develop polio.  Later, a live virus that could be given orally was developed, which actually did cause a few people to contract the disease.
Salk refused to patent his discovery, stating that he did not want to make money from it.  He wanted it readily available everywhere to protect children.

Oddly enough, because he built his research on previous research of other scientists and never publicly gave them credit. a jealousy developed in the medical community and he never received the Nobel Prize in medicine.
Nonetheless, he became an instant hero to parents around the world.  Today polio only poses a threat in a few African and Asian locales where people are still not widely vaccinated.


posted on July 18, 2012 5:12 AM ()

Comments:

Polio terrorized all of us.
comment by elderjane on July 18, 2012 2:33 PM ()
Yes, it did. I will never forget the precautions my parents and others tried to take, especially in the summer months.
reply by redimpala on July 18, 2012 5:16 PM ()
I am glad it's gone.
comment by kristilyn3 on July 18, 2012 11:40 AM ()
It's a horrible disease.
reply by redimpala on July 18, 2012 5:16 PM ()
Wouldn't it be great if the developers of new life-saving drugs had the same attitude as Dr. Salk? That would alleviate a great deal of the "medical insurance" crisis.
comment by jerms on July 18, 2012 7:22 AM ()
Had it been 2012 and there had been adverse effects, the mass tort lawyers would be rolling in the dough.
reply by jerms on July 18, 2012 7:45 AM ()
It certainly would. It would also alleviate a lot of suffering if new drugs didn't have to be tested for five years before the public could benefit from them. No one really know for sure if Salk's vaccine was going to wipe out polio or not. What they did know was that it was made from a dead virus and could not give polio to anyone. It was a crapshoot; but parents were so desperate they were willing to let their children have the immunization. Thank goodness it worked.
reply by redimpala on July 18, 2012 7:34 AM ()
Funny--in my 7 decades series I am about to get into my experiences being on the March of Dimes Board in Memphis.
comment by greatmartin on July 18, 2012 7:19 AM ()
People who did not live through those times have no idea how important and dedicated people were to the March of Dimes. People who had very little money still found a way to give for this cause.
reply by redimpala on July 18, 2012 7:38 AM ()

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